Video LectureNovel Approaches to ID Testing Using NGS-Based Metagenomics

Metagenomics, the genomic analysis of a population of microbes, enables the profiling of microbial communities in the environment and the human body at unprecedented depth and breadth. Its application in the diagnosis of infectious disease is enabling the rapid and accurate detection of thousands of pathogens in patient samples without the need for clinicians to suspect the likely cause and order the right test. This lecture discusses approaches, promises, and challenges for the use of metagenomics-based testing in the diagnosis and management of infectious syndromes.

Originally presented on March 20, 2018 in Salt Lake City, Utah.



Lecture Presenter

Robert Schlaberg, MD, Dr Med, MPH

Robert Schlaberg, MD, Dr Med, MPH

Medical Director, Microbial Amplified Detection, Virology, and Fecal Chemistry Laboratories
ARUP Laboratories
Assistant Medical Director, Virology, and Molecular Infectious Disease Laboratories
ARUP Laboratories
Assistant Professor of Clinical Pathology
University of Utah School of Medicine

Dr. Schlaberg is an assistant professor of pathology at the University of Utah School of Medicine. He received his MD and doctor medicinæ degrees at the Julius-Maximilians-University in Wuerzburg, Germany and his master of public health at the Mailman School of Public Health at Columbia University in New York City, where he also served as a postdoctoral fellow. Dr. Schlaberg trained in clinical pathology at the Columbia University College of Physicians & Surgeons, where he was the chief clinical pathology resident. He is certified in clinical pathology and medical microbiology by the American Board of Pathology. His research focuses on the use of next-generation sequencing for unbiased pathogen detection and host response-based diagnostics.



Objectives

After this presentation, participants will be able to:

  • Describe concepts of pathogen detection by metagenomic sequencing.
  • Summarize how metagenomics can be applied to infectious disease testing.
  • Identify strengths and limitations of metagenomic testing from a clinical perspective.

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories