Work Up of Acute Leukemia
Laboratory evaluation of acute leukemia although critical, is complex and is constantly evolving due to advancement in understanding the molecular basis of leukemia. Its implication is not only for diagnosis, but also for therapeutic and prognostic purposes. In recognition of the complexity of these testing algorithm, College of American Pathologists and American Society of Hematology have come up with guidelines to help clinician and pathologist in initial evaluation of acute leukemia. This presentation focuses on the classification, sample requirements and the tests needed on every patients as well as on a subset of patients. Prognostic and therapeutic implications of these newer molecular tests would be discussed briefly.
