Connect Sign InAnti-CD38 and Anti-CD47 Interference in the Blood Bank and Ways to Resolve Them
Biological therapies can be highly effective in treating malignancies but can cause interference with blood bank testing. Two monoclonal therapies directed at cluster designation antigens that cause red blood cell agglutination are highlighted: CD38 and CD47. This lecture will review the serologic reactivity and methods to abrogate blood bank interference.
Dr. Waseem Anani is the medical director of the ImmunohematologY Reference Laboratory and Blood Services at ARUP Laboratories, and an associate professor (clinical) for the University of Utah School of Medicine. He received his medical degree from Penn State College of Medicine. He then completed his residency in clinical pathology at the University of Pittsburgh and a fellowship in transfusion medicine from the Medical College of Wisconsin. Dr. Anani is board certified by the American Board of Pathology in clinical pathology and transfusion medicine. His research interests include glycomics and immunohematology.
