Non-neoplastic Kidney Pathology for the General Surgical Pathologist

The general surgical pathologist may encounter medical renal pathology in the course of daily work, including in the assessment of the non-neoplastic component of kidney resections for tumor, in the frozen section assessment of donor kidney biopsies prior to transplantation, and in the workup of the autopsy kidney. In this lecture, the goal is to highlight the most important associated renal pathology issues, and to cover practical aspects related to these three particular clinico-pathological scenarios.

Lecture Presenter
Marc Barry, MD
Marc Barry, MD
Associate Professor of Pathology (Clinical), University of Utah School of Medicine
Medical Director, Anatomic Pathology, ARUP Laboratories

Dr. Marc Barry is a medical director of anatomic pathology at ARUP Laboratories and an associate professor at the University of Utah School of Medicine. He received his medical degree from University College Dublin before completing an anatomic pathology residency at the Brigham and Women’s Hospital. Following his residency, Dr. Barry completed a post-doctoral research fellowship at the Massachusetts Institute of Technology. He then continued on to finish both a medical renal pathology fellowship and a urologic pathology fellowship at Brigham and Women’s Hospital. Dr. Barry is board certified in anatomic pathology and is affiliated with several professional organizations, including the United States and Canadian Academy of Pathology, the American Society for Clinical Pathology, and the College of American Pathologists. He is also the recipient of multiple awards, including the Registrar’s Prize for Research from the Royal Academy of Medicine in Ireland, the Research Scholarship Award from the College of American Pathology Foundation, and for Excellence in Urologic Resident Education from the University of New Mexico. Dr. Barry’s research interests include clinicopathologic questions in medical renal and urologic pathology as well as epidemiologic and translation aspects of urologic neoplasia.

Objectives

After this presentation, participants will be able to:

Recognize the most common pathologic findings in the non-neoplastic component of a nephrectomy or partial nephrectomy specimen (a component which is part of the CAP kidney tumor template), and to understand the potential clinical significance of these findings.
Describe the role of pathology in the workup of the donor kidney for transplantation, and to appreciate common findings at frozen section, and the clinical significance of these findings.
List common pathologic findings in the autopsy kidney, and to be able to differentiate between acute tubular injury and tubular autolytic artifact.