Molecular Diagnostics in Cytology and Small Biopsy Specimens of Non-Small Cell Lung Cancer
Non-small cell lung cancer is among the most common cancer types in males and females, in the US and worldwide, and currently has the highest mortality among all cancer types. Guidelines are continuously updated to reflect the most current state of knowledge on biomarker testing in this setting, and updated recommendations are in place as to what testing needs to be performed, based on pathological diagnosis and clinical presentation, along with what specimens can be tested and what characteristics the testing platforms utilized need to have. As the number of possibly actionable tests to be performed is increasing, it is important for the clinician and the pathologist to have an understanding of the clinical and technical aspect of this testing, in order to optimize the way specimens are procured and utilized for testing, especially in the setting of cytology and small biopsy specimens that are very common in lung cancer.
