Serology Testing in Multiple Myeloma

This lecture discusses the clinical presentation of patients with plasma cell dyscrasias and the assays used to support their diagnosis. Testing methodology and potential interferences are presented in the context of clinical case scenarios.

Lecture Presenter
Taylor S. Jackson, DO
Taylor S. Jackson, DO
Pathology Resident-PGY4, University of Utah School of Medicine

After completing his undergraduate degree from Utah State University, Dr. Jackson worked at ARUP Laboratories in the immunology division for nine years as a technologist/medical laboratory scientist. During this time, he completed two additional undergraduate degrees at the University of Utah in biology and medical lab science. He then attended medical school at Rocky Vista University at the Southern Utah University campus followed by a combined anatomic and clinical pathology residency. Following his residency, Dr. Jackson will complete a fellowship in hematopathology at the University of Utah.

Objectives

After this presentation, participants will be able to:

Contrast SPEP/IFE test methods and their combined use in generating an interpretation
Identify the clinical context when SPEP/IFE testing is indicated and what follow-up testing may be needed
Discuss potential test interferences caused by treatment of myeloma
Review treatment and management following diagnosis in clinical cases