Metagenomics for Universal Pathogen Detection
Metagenomics, the genomic analysis of a population of microorganisms, makes possible the profiling of microbial communities in the environment and the human body at unprecedented depth and breadth. Its rapidly expanding use is revolutionizing our understanding of microbial diversity in natural and man-made environments and is linking microbial community profiles with health and disease. In addition, recent progress in rapid and accurate data analysis has also demonstrated promise of metagenomics-based approaches for universal pathogen detection in routine patient samples. This lecture discusses approaches, promises, and challenges for the use of metagenomics-based tests in diagnostic laboratories.
