Connect Sign InPlatelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines
Platelet transfusion is a common intervention that has benefits and harms. It is intended to raise platelet counts in patients with thrombocytopenia or platelet dysfunction and therefore prevent or treat bleeding. New international platelet transfusion guidelines are now published in JAMA, with eleven recommendations in various clinical settings in favor of restrictive platelet transfusion strategies. Herein, the evidence, recommendations, and rationale are described.
Dr. Ryan A. Metcalf is section chief of Transfusion Medicine, medical director of the Blood Bank, inpatient chief value officer at University of Utah Health and ARUP Laboratories, and an associate professor (clinical) of pathology at the University of Utah School of Medicine. Dr. Metcalf graduated from the University of California Davis School of Medicine with a medical degree before completing an anatomic and clinical pathology and a fellowship in transfusion medicine at Stanford University. Dr. Metcalf is board certified in blood banking/transfusion medicine and in clinical pathology. His research interests include data-driven clinical transfusion medicine and data-driven quality management in medicine.
