Myelodysplastic Syndrome and Acute Myeloid Leukemia
The Myelodysplastic Syndromes (MDS) and acute leukemias of myeloid, erythroid, and megakaryocytic origin are clonal bone marrow disorders. They are characterized by clinical, morphologic, immunophenotypic and cytogenetic features. The most current and well-accepted classification of these disorders is from the World Health Organization (WHO) published in 2008. This presentation will review these disorders with an emphasis on the pathologic diagnosis of each, including the use of laboratory methods for classification, management and prognostic assessment.
