Prion Disease History and Transmission in a Medical Setting
For decades, prion disease has been of great concern to doctors, but it made headlines in the 1980s and 1990s because of mass infections of cattle in Great Britain. This led to the destruction of millions of cows and caused concern regarding the consumption of potentially infected beef. Although rare, human infection by abnormal prion proteins can cause Creutzfeldt-Jakob disease (CJD), Kuru and other transmissible spongioform encephalopathies. In this lecture Dr. Hale presents a brief history of what is known about prion proteins, their structure, infectivity, and the current state of prion diseases as well as strategies for working with possibly infectious specimens or materials in a healthcare setting.
