AACC 2017 Booth Presentation: Inflammatory Myopathies— A Laboratory Update on Autoantibody Testing
Inflammatory myopathies (IM) are rare and heterogeneous in clinical presentation and associated with diverse autoantibody targets. Most autoantibodies target intracellular proteins, including nuclear and cytoplasmic antigens and, based on their specificity, can be grouped into myositis-specific and myositis-associated autoantibodies. Testing methods have lagged behind those of the more common connective tissue diseases. This session will describe the use of specific autoantibodies and methods for defining clinical categories of IM, indications for testing, as well as implications for more personalized management.
