Connect Sign InRespiratory transfusion reactions occur less frequently than allergic or febrile nonhemolytic transfusion reactions; however, they account for the highest number of transfusion-related fatalities, as actively reported to the FDA in the United States. They are also likely to occur at a rate of 5 to10 times more frequently than the rate currently being passively reported. Careful assessment of patients before, during, and after transfusion is key to mitigating and treating respiratory transfusion reactions. This case-based educational review of transfusion-associated circulatory overload (TACO) and transfusion-related acute lung injury (TRALI) covers the basics of these entities with a practical approach to clinical understanding.
Presented by
Joel Addams, MD
Assistant Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Transfusion Medicine, ARUP Laboratories
Erica Swenson, DO
Assistant Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Transfusion Medicine, ARUP Laboratories
