ARUP Laboratories University of Utah Department of Pathology FDLC Logo Radboudumc Logo Atlas Logo

Provisional Program

Monday (8/31): The fungal Kingdom; Introduction

Registration and Breakfast: 7:15 am

Lectures: 8:00-9:35 am and 9:45 am-12:45 pm (4.5 hours)

  • 8:00-8:05: Course Directors: Welcome & Introduction
  • 8:05-9:05: Sybren de Hoog: General taxonomy; life cycles; pleomorphism, nomenclature
  • 9:05-9:35: Sybren de Hoog/Thomas Walsh/Sean Zhang: Taxonomy and solutions for nomenclatural stability
  • 9:35-9:45: Break
  • 9:45-10:45: Sybren de Hoog: Introduction to Atlas of Clinical Fungi; diagnostic keys
  • 10:45-11:15: Sybren de Hoog: Introduction to microscopic methods
  • 11:15-12:15: Thomas Walsh: The host, who are at risk for fungal diseases?

Lunch: 12:15-1:00 pm

Lectures: 1:00-3:00 pm and 3:15-5:15 pm (4.0 hours)

  • 1:00-1:30: Sean Zhang: Principles and procedures for detection and culture of fungi in clinical specimens
  • 1:30-2:00: Sean Zhang: Direct microscopic examination on clinical specimens
  • 2:00-3:00: Mariana Castanheira: Practice of antifungal drug testing, MIC readings, and ECVs
  • 3:00-3:15: Break
  • 3:15-4:15: Shawn Lockhart: Antifungal drug acquired and intrinsic resistance
  • 4:15-5:15: Nathan Wiederhold: PK/PD of antifungals, antifungal therapeutic monitoring, new antifungal drugs and their nuances in AFST

    • Tuesday (9/1): Mucorales and Entomophthorales & Eurotiales (Hyaline hyphomycetes I)

    Breakfast: 7:15 am

    Lectures: 8:00-10:00 am and 10:15 am-12:45 pm (4.5 hours)

    • 8:00-9:00: Lars Westblade: Taxonomy, colony, and microscopic features of the Mucorales and Entomophthorales
    • 9:00-10:00: Thomas Walsh: Infections by Mucorales and Entomophthorales
    • 10:00-10:15: Break
    • 10:15-10:30: Sybren de Hoog: Short introduction to ascomycetes
    • 10:30-11:00: Sybren de Hoog: Conidiogenesis in asexual fungi: hyphomycetes and coelomycetes
    • 11:00-11:45: Sybren de Hoog: Taxonomy, colony, and microscopic features of Eurotiales: Aspergillus, Paecilomyces, Talaromyces
    • 11:45-12:45: Barbara Alexander: Aspergillosis

    Lunch: 12:45-1:45 pm

    1:00-1:15: OPTIONAL Non-CME Product Theater: Industry presentation
    1:25-1:40: OPTIONAL Non-CME Product Theater: Industry presentation

    Practice: 1:45-3:30 pm and 3:45-5:15 pm (3.25 hours)

    • 1:45-1:55: Introduction: common lab tools and techniques for fungal identification (Rachel Green, Warda Memon)
    • 1:55-3:30: Microscopy mucormycetes (Lichtheimia ramosa, Cunninghamella bertholletiae, Mucor circinelloides, Mucor velutinosus, Rhizopus arrhizus, Syncephalastrum racemosum, Rhizomucor pusillus)
    • 3:30-3:45: Break
    • 3:45-5:15: Microscopy of Eurotiales (Aspergillus fumigatus, Aspergillus terreus, Aspergillus calidoustus, Paecilomyces variotii, Purpureocillium lilacinum [Paecilomyces lilacinus] Rasamsonia argillacea, Talaromyces purpureogenus [Penicillium purpurogenum])

    Welcome Dinner: 6:30 pm – Location TBD

    Wednesday (9/2): Onygenales (Dermatophytes & Dimorphic fungi)

    Breakfast: 7:45 am

    Lectures: 8:30-9:45 am and 10:00 am-12:45 pm (4 hours)

    • 8:30-9:00: Sybren de Hoog: Introduction to ecology of primary and opportunistic pathogens
    • 9:00-9:45: Amir Seyedmousavi: Taxonomy, colony, and microscopic features of Arthrodermataceae (dermatophytes)
    • 9:45-10:00: Break
    • 10:00-11:00: Avrom Caplan: Dermatophyte infections, a Dermatologist’s Perspective
    • 11:00-11:45: Tanis Dingle: Ajellomycetaceae: agents of endemic mycoses – dimorphic fungi
    • 11:45-12:45: George Thompson: Coccidioidomycosis, Paracoccidioidomycosis, Blastomycosis, Histoplasmosis, Emergomycosis, Talaromycosis

    Lunch: 12:45-1:45 pm

    1:00-1:15: OPTIONAL Non-CME Product Theater: Industry presentation
    1:25-1:40: OPTIONAL Non-CME Product Theater: Industry presentation

    Practice: 1:45-3:30 pm and 3:45-5:15 pm (3.25 hours)

    • 1:45-3:30: Microscopy Dermatophytes (Epidermophyton floccosum, Microsporum canis, Nannizzia gypsea [Microsporum gypserum], Trichophyton interdigitale, Trichophyton indotineae, Trichophyton rubrum, Trichophyton tonsurans, Trichophyton [Arthroderma] benhamiae)
    • 3:30-3:45: Break
    • 3:45-4:45: Microscopy review of endemic mycoses (Histoplasma capsulatum, Coccidioides immitis/posadasii, Blastomyces dermatitidis): mold and yeast forms
    • 4:45-5:15: Blaine Mathison: Microsporidia

      • Thursday (9/3): Yeasts and Yeast-like fungi

      Breakfast: 7:45 am

      Lectures: 8:30-10:30 am and 10:4 5am-12:45 pm (4 hours)

      • 8:30-9:30: Sybren de Hoog: Overview of yeasts and yeast-like fungi
      • 9:30-10:30: Hong Nguyen: Candidiasis
      • 10:30-10:45: Break
      • 10:45-11:45: Kimberly Hanson: Cryptococcosis
      • 11:45-12:45: Gary Procop: Pneumocystis

      Lunch: 12:45-1:45 pm

      1:00-1:15: OPTIONAL Non-CME Product Theater: Industry presentation
      1:25-1:40: OPTIONAL Non-CME Product Theater: Industry presentation

      Practice: 1:45-3:30 pm and 3:45-5:15 pm (3.25 hours)

      • 1:45-2:45: Microscopy of ascomycetous yeasts (Candida albicans, Candida glabrata [Nakaseomyces glabrataa], Candida krusei [Pichia kudriavzevii], Candida tropicalis, Candida parapsilosis, Candida auris, Magnusiomyces capitatus [Saprochaete capitata], Geotrichum candidum)
      • 2:45-3:30: Microscopy of basidiomycetous yeasts (Cryptococcus neoformans, Cryptococcus gattii, Malassezia furfur, Trichosporon asahii, Rhodotorula mucilaginosa), and yeast-like (Prototheca wickerhamii).
      • 3:30-3:45: Break
      • 3:45-4:30: Patricia Slev: Fungal serology testing
      • 4:30-5:15: Sean Zhang: Current diagnostic techniques – MALDI-TOF MS, antigen testing, molecular and sequencing identification

      Tour of ARUP Laboratories: 5:45 pm – Meet in hotel lobby for the 5-minute walk to ARUP

      Friday (9/4): Black yeasts and other dematiaceous opportunists

      Breakfast: 7:45 am

      Lectures: 8:30-10:30 am and 10:45 am-12:45 pm (4 hours)

      • 8:30-9:30: Sybren de Hoog: Taxonomy, colony, and microscopic features of black yeasts and relatives; diagnostic overview
      • 9:30-10:30: Sybren de Hoog: Clinical pictures of black yeasts and relatives.
      • 10:30-10:45: Break
      • 10:45-11:30: Dallas Smith: Chromoblastomycosis & Phaeohyphomycosis
      • 11:30-12:15: Sybren de Hoog: Mycetoma, melanized opportunists in Pleosporales (dematiaceae, coelomycetes)
      • 12:15-12:45: Sybren de Hoog: Microascales: Scedosporium and brain infection.

      Lunch: 12:45-1:45 pm

      1:00-1:15: OPTIONAL Non-CME Product Theater: Industry presentation
      1:25-1:40: OPTIONAL Non-CME Product Theater: Industry presentation

      Practice: 1:45-3:30 pm and 3:45-5:45 pm (3.75 hours)

      • 1:45-3:30: Microscopy of traumatic Chaetothyriales (Exophiala dermatitidis, Cladophialophora boppii, Phialophora verrucosa, Rhinocladiella similis, Fonsecaea monophora) and Microascales (Lomentospora [Scedosporium] prolificans, Scedosporium apiospermum), Capnodiales (Cladosporium cladosporioides)
      • 3:30-3:45: Break
      • 3:45-5:45: Microscopy of Pleosporales (Alternaria alternata, Curvularia geniculata, Bipolaris spicifera, Exserohilum rostratum, Phoma herbarum), Sodariales (Phialemonium atrogriseum, Madurella mycetomatis), Venturiales (Verruconis gallopava)

      Saturday (9/5): Hyaline opportunists (Hyaline hyphomycetes II) and Basidiomycetes

      Breakfast: 7:45 am

      Lectures: 8:30-10:30 am and 10:45 am-12:45 pm (4 hours)

      • 8:30-9:00: Sybren de Hoog: Ophiostomatales: Sporothrix and sporotrichosis
      • 9:00-10:00: Sybren de Hoog: Hypocreales: Fusarium and relatives
      • 10:00-10:15: Break
      • 10:15-11:15: Sybren de Hoog: Basidiomycetous filamentous fungi
      • 11:15-12:15: Ben Bradley: Fungal histopathology
      • 12:15-12:45: Sybren de Hoog: Overview of pathogenicity in the fungal kingdom

      Lunch: 12:45-1:45 pm

      Practice: 1:45-3:15 pm and 3:30-5:00 pm (3 hours)

      • Microscopy of filamentous Basidiomycetes (Schizophyllum commune, Phanerochaete chrysosporium [Sporotrichum pruinosum])
      • Microscopy of Hypocreales (Fusarium oxysporum, Fusarium solani, Fusarium proliferatum, Sarocladium [Acremonium] kiliense, Acremonium egyptiacum)
      • Microscopy of Ophiostomatales (Sporothrix schenckii)
      • 3:15-3:30: Break
      • 3:30-5:00: Sean Zhang & Kimberly Hanson: Case studies

      Certificates and Farewell: 5:00-5:15 pm

      All course sessions will be located on the lower level of the Salt Lake City Marriott – University Park

      • Lectures will take place in Ballroom 1
      • Practice sessions will take place in Ballroom 2/3 (please bring your laptop and a lab-coat)
      • Product Theater presentations will take place in the Connor Room
      • Breakfast/Lunch/Breaks will be available in the Atrium

      Course Disclaimer:
      Attendance does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught at this course.

      Conference Cancellation Policy:
      The University of Utah Department of Pathology and ARUP Laboratories reserves the right to cancel or postpone this conference due to unforeseen circumstances. In the unlikely event of a cancellation or postponement of this conference, registration fees will be refunded in full; however, the University of Utah Department of Pathology and/or ARUP Laboratories is not responsible for any other related costs, charges, or expenses incurred by registrants of this conference.