Molecular Diagnosis of Gliomas

 

The importance of molecular alterations in gliomas has long been recognized. Accordingly, the new WHO Classification of CNS Tumors has incorporated many molecular alterations into the diagnostic algorithms used for primary gliomas. This lecture will describe these alterations, their diagnostic and/or prognostic significance, and the molecular testing modalities that detect them.

Originally presented on February 7, 2022, in Park City, Utah.

Lecture Presenter

Christian J. Davidson, MD

Christian J. Davidson, MD

Assistant Professor of Pathology
University of Utah School of Medicine
Medical Director, Anatomic Pathology
ARUP Laboratories

Dr. Davidson is an assistant professor of pathology at the University of Utah School of Medicine. After receiving his MD from Jefferson Medical College in Philadelphia, he completed his anatomic pathology residency training at Brigham and Women’s Hospital and his neuropathology fellowship at Massachusetts General Hospital, both in Boston. Dr. Davidson is a member of the American Association of Neuropathologists. In addition, he has a longstanding interest in molecular tumorigenesis of brain tumors, specifically the diffuse gliomas and NF2-related tumors.

Objectives

After this presentation, participants will be able to:

  • Identify the histopathology of common glial tumors
  • Describe the diagnostic molecular alterations present in these tumors
  • Recognize the changes made to the WHO classification and grading system of these tumors
  • Implement a diagnostic algorithm to aid in your diagnosis of CNS tumors

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories