MLS Topics

This presentation will explore the role of AI in select cases of parasitology along with future applications of AI moving forward.

Presented by 
Blaine A. Mathison, BS, M(ASCP)
Adjunct Instructor, Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Technical Director of Parasitology, ARUP Laboratories

This video is 55 min

An 86 year-old male, O+, with a history of anemia presented with extreme fatigue in 2020 and significant weight loss. BMBx found erythroid megloblasoid maturation and abnormal cytogenetics. Diagnosed with low-grade Myelodysplastic syndrome. Severe anemia a year later, repeated BMBx and did not met MDS criteria. This presentation will further discuss the patient's case and labs along with diving into autoimmune hemolytic anemia.

Presented by 
Taylor S. Jackson, DO
Pathology Resident-PGY4; Spencer Fox Eccles School of Medicine at the University of Utah

This video is 18 min

A manual examination of cellular morphology on a stained peripheral blood smear is still an important, and increasingly "lost" skill, useful in the evaluation of patients with hematologic abnormalities. This presentation provides helpful hints to aid the review of blood smears by describing staining properties of various cells and cellular structures, discussing morphologic features that distinguish mature and immature leukocytes, and suggesting strategies to differentiate morphologic look-alikes.

Presented by
Karen A. Brown, MS, MASCP, MLS(ASCP)^CM
Clinical Coordinator, Medical Laboratory Sciences, Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah; Professor of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 58 min

Note: This video shows graphic medical images from actual bone marrow biopsy procedures.This video provides a basic overview to a bone marrow biopsy procedure.

Developed by the Institute for Learning, ARUP Laboratories

This video is 6 min

An 81 year old, B positive female with a history of hemochromatosis, multiple sclerosis, IBS and was recently diagnosed with AML presents with a WBC 2.83k/uL, Hgb 7.5 g/dL, and platelets 6,000/uL. This case review will discuss human leukocyte antigens and how HLA antibodies affect transfusions.

Presented by
Taylor S. Jackson, DO
Pathology Resident-PGY4; Spencer Fox Eccles School of Medicine at the University of Utah

This video is 13 min

This presentation will cover fun, bizarre cases in Parasitology. The route of infection for various foodborne parasites and the clinical presentation of zoonotic parasites will be discussed.

Presented by
Blaine A. Mathison, BS, M(ASCP)
Adjunct Instructor, Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Technical Director of Parasitology, ARUP Laboratories

This video is 54 min

This lecture will cover some entities that require genetic testing for precise diagnosis and classification, as opposed to cases where the diagnosis is based only on morphology and immunophenotype.

Presented by
Rodney R. Miles, MD, PhD
Professor, Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology, ARUP Laboratories

This video is 54 min

This lecture will cover the basic diagnosis of CLL/SLL. Additionally, recommended testing and a review the effects of targeted therapies on various assays will be discussed.

Presented by
David P. Ng, MD, FCAP
Associate Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director: Hematopathology, Hematologic Flow Cytometry, Applied Artificial Intelligence and Bioinformatics, ARUP Laboratories

This video is 42 min

This lecture will discuss cytogenetics and leukemias and will focus on Acute Lymphocytic/Lymphoblastic Leukemia (ALL), Mature B-Cell Leukemias, and Mature T-cell and NK-cell Leukemias.

Presented by
Jill Johnston, BS CG(ASCP)^CM
Cytogenetic Technologist Specialist, Cytogenetics, ARUP Laboratories

This video is 36 min

This lecture will explain cytogenetics and leukemias with a focus on Chronic Myelogenous Leukemia (CML), Myelodysplastic Syndrome (MDS), and Acute Myelogenous Leukemia (AML).

Presented by
Jill Johnston, BS CG(ASCP)^CM
Cytogenetic Technologist Specialist, Cytogenetics, ARUP Laboratories

This video is 25 min

The understanding of anemias is very important as clinicians attempt to provide high quality medical care to their patients. The medical laboratory scientist must also understand anemias to provide this needed information. This lecture will address the basics for the classification of anemias and tools used in the medical laboratory to assess a patient’s blood health or presence of anemia.

Presented by
Archana Mishra Agarwal, MD
Professor (Clinical), Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology and RBC Laboratory, ARUP Laboratories

This video is 1 hr 14 min

This video provides a basic overview on how to dilute a whole blood speciment for cell counts using a hemacytometer.

Developed by the Institute for Learning, ARUP Laboratories

This video is 4 min

Zoonotic diseases represent an ongoing risk to humans, especially with increased interactions between animals, vectors, and humans. This narrative case series explores the variety of zoonotic diseases that can be encountered in North America and discusses appropriate diagnostic testing strategies and tips and tricks to predict these zoonoses.

Presented by 
Marc Roger Couturier PhD, D(ABMM)
Former Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Former Head of Clinical Operations for Clinical Microbiology and Immunology; Medical Director, Emerging Public Health Crises, Parasitology/ Fecal Testing, and Infectious Disease Antigen Testing, ARUP Laboratories

This video is 39 min

Hematology instrumentation has advanced to now routinely include at least a five-part differential and, in some laboratories, automated cell image analysis. Yet, a manual examination of the blood smear is still an essential procedure that provides valuable diagnostic information. This session will use case studies to define important morphologic variations and physiologic processes in selected disease conditions.

Presented by 
Karen A. Brown, MS, MASCP, MLS(ASCP)^CM
Clinical Coordinator, Medical Laboratory Sciences, Department of Pathology, Professor of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 45 min

Hematology instrumentation has advanced to now routinely include at least a five-part differential and, in some laboratories, automated cell image analysis. Yet, a manual examination of the blood smear is still an essential procedure that provides valuable diagnostic information. This session will use case studies to define important morphologic variations and physiologic processes in selected disease conditions.

Presented by 
Karen A. Brown, MS, MASCP, MLS(ASCP)^CM
Clinical Coordinator, Medical Laboratory Sciences, Department of Pathology, Professor of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 45 min

A 65 year-old male, O+, admitted with a small bowel obstruction for 4 days. Two weeks later presented to ED with abdominal pain, chills, fatigue, etc. Lab reported hemolysis. Imaging showed hepatic abscess and cholecystitis. This presentation will further discuss the patient's labs and findings along with explore hemolysis and clostridium perfringens infection.

Presented by
Taylor S. Jackson, DO
Pathology Resident-PGY4; Spencer Fox Eccles School of Medicine at the University of Utah

This video is 14 min

This video will instruct you how to create a basic manual blood smear.

Developed by the Institute for Learning, ARUP Laboratories

This video is 3 min

This video will instruct you on how to create a manual Wright stain.

Developed by the Institute for Learning, ARUP Laboratories

This video is 3 min

A 70-year-old male presents with on-going nosebleeds. They have a history of hypertension, diabetes mellitus type 2, gout, cronic sinusitis, aortic stenosis s/p aortic valve repair. Diagnosted with ITP ~ 5 to 10 years ago on rituximab. This presention will discuss this patient's diagnosis along with diving into immune thrombovytopenia.

Presented by 
Miranda Chimzar, MD
Pathology Resident-PGY2, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 16 min

37 year-old women at 29 weeks pregnant, type A+, 4 cm placental mass, polyhydramnios, and new concern for fetal anemia based on elevated MCA dopplers was admitted to be consulted for amnioreduction and intrauterine transfusion. This presention will further discuss this case along with explore intrauterine RBC transfusions in more detail.

Presented by
David Anderson, DO
Pathology Resident-PGY1 AP/CP, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 17 min

This presentation will discuss the principles of flow cytometry, components of the flow cytometer, and applications in the diagnosis and treatment of disease.

Presented by 
John Andreasen, MLS(ASCP)
Laboratory Supervisor, Immunologic Flow Cytometry, ARUP Laboratories

This video is 38 min

This presentation will review the pathophysiology, clinical and laboratory findings, and recent advances in the field of hemoglobinpathies and thalassemias. It will also highlight laboratory testing methodologies including high-performance liquid chromatography (HPLC), capillary electrophoresis, and molecular analysis to diagnose thalassemias.

Presented by 
Archana Mishra Agarwal, MD
Professor (Clinical), Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology and RBC Laboratory, ARUP Laboratories

This video is 51 min

This video provides a basic overview on how to load a hemacytometer for manual cell count.

Developed by the Institute for Learning, ARUP Laboratories

This video is 4 min

This lecture will discuss the morphologic features of abnormal lymphocytes in the peripheral blood and the importance of initial evaluation for the diagnostic work up. An explanation of normal T- and B- cell development and a review of ICSH recommendations for the standardization of nomenclature of lymphocytes will be provided.

Presented by
Anton V. Rets, MD, PhD
Assistant Professor (Clinical) of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology, ARUP Laboratories

This video is 55 min

Phlebotomists routinely encounter dangerous conditions, problem patients, and other issues during blood collection. This session will suggest techniques that can help you avoid or safely manage these difficulties. Areas to be discussed include:

• risks associated with venous blood collection, such as improper vein selection and needlestick exposure
• unusual patient situations that impact phlebotomy practice, including the cancer and bariatric patient
• communication barriers and methods to improve patient interactions, like developing good listening skills and effective communication approaches with the elderly

Designed for phlebotomists and phlebotomy students who have comprehension of the basics of the venipuncture technique, this session will enhance your skills, build your knowledge base, and help you deliver the highest quality in patient care.

Presented by 
Karen A. Brown, MS, MASCP, MLS(ASCP)^CM
Clinical Coordinator, Medical Laboratory Sciences, Department of Pathology, Professor of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 60 min

A 61 year-old male with HTN transferred from an OSH with MET, acidosis, AKI, and hypoglycemia in the setting of severe malaria and an incidental COVID infection 5 days after returning from Mazambique. No malaria prophylaxis taken. Smear showed Plasmodium falciparum, parasitemia, 24.4%, for which he was started on Artesunate q12h x3 doses, then daily until parasitemia was <1% followed by coatem BID x3 days. Post coatem, he began to feel more fatigued with intermittent mild fevers and darkening urine. He became HDS and aferbrile, but his CBC was notable for a Hgb of 5.1 with PLT of 363. This presentation will further explore this case along with discussing post-artesunate delayed hemolysis in greater detail.

Presented by
David Anderson, DO
Pathology Resident-PGY1 AP/CP, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 21 min

This presentation will provide a brief tutorial focusing on interpretation of red blood cell shape abnormalities and discussing common associated pathologic conditions.

Presented by 
Anton Rets, MD, PhD
Associate Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology, ARUP Laboratories

This video is 20 min

This presentation will provide a brief tutorial focusing on interpretation of red blood cell size, color, and their distribution in the smear and a discussion of common abnormalities and their clinical significance.

Presented by
Anton Rets, MD, PhD
Associate Professor (Clinical), Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology, ARUP Laboratories

This video is 25 min

This is a basic overview of malaria and the causative agent, Plasmodium species. This lecture will cover the life cycle of the parasite, the species' differentiating characteristics in the human host, and case studies for Plasmodium falciparum. P. ovale, P. vivax, P. malariae. 

Presented by
DeVon C. Hale, MD
Assistant Dean of International Medical Education, Professor of Internal Medicine, Professor of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 48 min

This lecture discusses the clinical presentation of patients with plasma cell dyscrasias and the assays used to support their diagnosis. Testing methodology and potential interferences are presented in the context of clinical case scenarios.

Presented by
Taylor S. Jackson, DO
Pathology Resident-PGY4, Spencer Fox Eccles School of Medicine at the University of Utah

This video is 57 min

This lecture will address different types of RBC membrane disorders including hereditary spherocytosis (HS), hereditary elliptocytosis (HE), hereditary pyropoikilocytosis (HPP), and hereditary stomatocytosis (HSt). This lecture will also discuss these disorders’ pathophysiology and utilization of NGS for diagnostic identification.

Presented by
Archana Mishra Agarwal, MD
Professor (Clinical), Department of Pathology, Spencer Fox Eccles School of Medicine at the University of Utah
Medical Director, Hematopathology and RBC Laboratory, ARUP Laboratories

This video is 51 min

This video will review cases involving unusual and interesting organisms one might encounter in the clinical microbiology laboratory.

Presented by
Lars Westblade, PhD, D(ABMM)
Associate Professor of Pathology and Laboratory Medicine, Associate Professor of Pathology and Laboratory Medicine in Medicine (Infectious Diseases), Director, Clinical Microbiology, Weill Cornell Medicine, Cornell

This video is 1 hr 1 min