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Classification of Leukemias and Lymphomas: Increasing Role of Molecular Testing



 

This presentation will cover some entities that require genetic testing for precise diagnosis and classification, as opposed to cases where the diagnosis is based only on morphology and immunophenotype.

Originally presented on June 15, 2020, in Salt Lake City, Utah.


Lecture Presenter

Rodney R. Miles, MD, PhD

Rodney R. Miles, MD, PhD

Associate Professor
University of Utah School of Medicine
Section Chief: Hematopathology; Medical Director: Hematologic Flow Cytometry, Immunohistochemistry Laboratory
ARUP Laboratories

Dr. Miles is the Section Chief of Hematopathology at ARUP Laboratories and an associate professor of pathology at the University of Utah School of Medicine. Dr. Miles received his MD and a PhD in cell biology from the University of Nebraska. He is certified by the American Board of Pathology in anatomic and clinical pathology, with subspecialty certification in hematology. His research interests include pediatric non-Hodgkin lymphoma and acute lymphoblastic leukemia.

Dr. Miles is a member of the American Society of Hematology, the Society for Hematopathology, and the United States and Canadian Academy of Pathology. He is a member of the Children's Oncology Group non-Hodgkin lymphoma committee and serves as a central pathology reviewer for clinical trials.


Objectives

After this presentation, participants will be able to:

  • Describe how molecular and cytogenetic findings are used to more precisely classify leukemia and lymphoma
  • Identify how molecular and cytogenetic findings add prognostic information which may evolve into classification in the future
  • Discuss clonal hematopoiesis and “pre MDS”
  • Recognize how molecular and/or cytogenetic data were used to classify leukemia and lymphoma or add prognostic information in cases

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories