What You Inhale Can Kill You


The presentation summarizes what we know thus far about the pathology of vaping-related lung injury. There are only a few pathologic studies on the types of lung damage that occur in vaping and the differences between these and smoking-related changes. We will discuss the striking histologic differences in lung injury caused by these two dangerous inhalational exposures.

Originally published on November 3, 2021

Lecture Presenter

Sanjay Mukhopadhyay, MD

Sanjay Mukhopadhyay, MD

Director of Pulmonary Pathology
Cleveland Clinic

Dr. Mukhopadhyay is Director of Pulmonary Pathology at the Cleveland Clinic and Associate Editor (Pulmonary) of the American Journal of Clinical Pathology. He attended medical school in India and completed pathology residency training at the All India Institute of Medical Sciences followed by a second pathology residency at SUNY Upstate Medical University (Syracuse, NY). After a pulmonary pathology fellowship at the Mayo Clinic (Rochester, MN), he was recruited back to Syracuse and stayed on as faculty for next 6 years, rising to the rank of tenured Associate Professor in 2011. In 2013, he joined the department of pathology at the Cleveland Clinic. His interests include granulomatous lung diseases (including infections), interstitial lung disease, and lung cancer. The pulmonary pathology service at Cleveland Clinic signs out 5000 cases a year and supports a large group of ILD pulmonologists and several thoracic surgeons. The lung transplant service is one of the busiest in the world.

Dr. Mukhopadhyay has authored more than 100 publications in indexed, peer-reviewed journals, and is the author of a lung pathology textbook published by Cambridge University Press in 2016. His studies have been published in the American Journal of Surgical Pathology, American Journal of Clinical Pathology, Modern Pathology, Human Pathology, Chest and Thorax. In 2011, he was invited to join the faculty of the prestigious USCAP Long Course in Pulmonary Pathology. He has received several teaching awards, served on the abstract review committees of the USCAP and CAP for several years, moderated platform sessions at USCAP, and taught two USCAP Short Courses. Since 2016, he has pioneered the use of online platforms for teaching lung pathology globally, first-authored a landmark study that led to FDA approval for whole slide imaging for primary diagnosis in surgical pathology in the United States, and authored studies of the effects of vaping on the lung and autopsy findings in COVID-19 that have generated intense interest in the media and online. Dr. Mukhopadhyay was recently featured in a New York Times video on COVID-19 and ARDS that has been viewed more than 1.3 million times.


After this presentation, participants will be able to:

  • Recognize the morphologic features of lung damage caused by vaping
  • Describe the differences between the pathology of vaping and smoking
  • Recognize the limitations of oil red O staining for the diagnosis of vaping-related lung disease

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories