Laboratory Diagnosis of Polycystic Ovary Syndrome (PCOS)


Polycystic ovarian syndrome (PCOS) is a complex endocrine-mediated disorder affecting women in their reproductive age. It is also one of the leading causes of anovulatory infertility. The pathophysiology of PCOS is still not entirely understood; however, androgen excess and insulin-resistant have been proposed as possible pathologic mechanisms for PCOS. The diagnosis of PCOS is predominately a diagnosis of exclusion because other clinical conditions may have signs and symptoms similar to PCOS. This presentation will review the key diagnostic features of PCOS and summarize the relevant laboratory tests for the evaluation of suspected PCOS.

Originally presented on May 31, 2021, in Salt Lake City, Utah.

Lecture Presenter

Nkem Okoye, PhD

Nkem Okoye, PhD

Clinical Chemistry Fellow
University of Utah Department of Pathology

Dr. Nkem Okoye is a clinical chemistry fellow at the University of Utah Department of Pathology and ARUP Laboratories. He graduated with a BS in Chemistry from South Carolina State University. Dr. Okoye subsequently earned his PhD in Chemistry from the University of Missouri-Columbia where he worked on the synthesis and preclinical evaluation of peptide receptor-targeted radiopharmaceuticals for diagnostic imaging and therapy of prostate cancer.


After this presentation, participants will be able to:

  • Describe the common signs and symptoms associated with PCOS
  • Define the Rotterdam criteria for PCOS diagnosis
  • List the laboratory tests for evaluation of suspected PCOS

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories