Surprise! Breast Tumors with Unexpected Final Pathology


This talk is organized in two parts to discuss pathology cases with similar morphology, but different diagnoses. Part 1 focuses on variants of invasive lobular carcinoma, their prognostic differences, and their mimics. Part 2 focuses on neuroendocrine tumors of the breast, how they are classified and diagnosed, and includes a discussion of small cell carcinoma and adenoid cystic carcinoma, a rare mimic of neuroendocrine tumors in the breast.

Originally presented on February 10, 2015, in Park City, Utah.

Lecture Presenter

Rachel E. Factor, MD, MHS

Rachel E. Factor, MD, MHS

Associate Medical Director, Cytopathology and Surgical Pathology
ARUP Laboratories
Assistant Professor of Pathology
University of Utah School of Medicine

Dr. Factor is a staff pathologist and a medical director in the Cytology Laboratory at ARUP and an assistant professor of pathology at the University of Utah Health Sciences Center. Dr. Factor received her master of health science from Johns Hopkins School of Public Health and her MD from the Albert Einstein College of Medicine in Bronx, New York. She completed an internship in internal medicine at NYU Medical Center and a residency in anatomic pathology followed by fellowships in surgical pathology and cytopathology at Brigham and Women's Hospital in Boston. Dr. Factor is board certified in anatomic pathology and cytopathology, and is a member of the College of American Pathology, United States and Canadian Academy of Pathology, and the American Society for Clinical Pathology. Her research interests include topics in breast pathology and cytopathology.


After this presentation, participants will be able to:

  • Review lobular carcinoma and variants.
  • Review mimics of lobular carcinoma.
  • Discuss work-up of primary vs metastatic disease.
  • Review classification of neuroendocrine tumors of the breast.
  • Review primary vs metastatic neuroendocrine tumors.
  • Discuss rare tumors of the breast: small cell carcinoma and adenoid cystic carcinoma.

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories