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Autoantibody Testing in the Diagnosis of Autoimmune Neurological Disorders


Autoimmune neurology is a rapidly evolving field, with additional autoantibodies continually being identified. This presentation will focus on the laboratory’s role in diagnosing and managing autoimmune neurologic disorders, including paraneoplastic neurological syndromes (PNS), autoimmune encephalitis, and autoimmune neuromuscular junction disorders. Also discussed will be methods for detecting autoantibodies in serum and CSF, with an emphasis on their strengths and weaknesses, as well as testing strategies for autoimmune neurologic diseases.

Originally presented on July 24, 2017 at Salt Lake City, Utah.


Lecture Presenter

Lisa K. Peterson, PhD
Lisa K. Peterson, PhD
Instructor of Pathology, University of Utah School of Medicine
Medical Director, Immunology, ARUP Laboratories

Dr. Peterson is an instructor of pathology at the University of Utah School of Medicine. She received her PhD in experimental pathology from the University of Utah and completed a postdoctoral fellowship in the Department of Immunology at National Jewish Health and the University of Colorado School of Medicine in Denver. Dr. Peterson continued her training with a clinical immunology fellowship at the University of Utah. Her research interests include cellular immunology and autoimmune immunology, with a focus on autoimmune neurology. Dr. Peterson is a member of the Association of Medical Laboratory Immunologists, the Clinical Immunology Society, and the American Society for Microbiology.


Objectives

After this presentation, participants will be able to:
  • Understand the role of autoantibody testing in diagnosis and management of autoimmune neurologic disorders.
  • Compare and contrast methods used to detect the relevant autoantibodies.
  • Describe different strategies for autoantibody testing.

Sponsored by:

Spencer Fox Eccles School of Medicine at the University of Utah, Department of Pathology, and ARUP Laboratories