Beyond A, B, and C: Emerging and Reemerging Infections in the Liver

This lecture offers the following credit types: CME, P.A.C.E.®, Florida
 

In the dynamic field of infectious disease pathology, pathologists play a pivotal role in the diagnosis of emerging and reemerging infections. This interactive lecture describes the histopathologic features of several emerging and reemerging infections that involve the liver and describes how to synthesize clinical and laboratory data to narrow the differential diagnosis of active hepatitis and select appropriate ancillary tests. Two of the case presentations will also help pathologists expand the differential diagnosis of hepatic granulomata, while one of the cases will provide key updates on an emerging infection that may be underdiagnosed in the United States.

Originally published on August 5, 2025

Lecture Presenter

Gillian L. Hale, MD, MPH

Gillian L. Hale, MD, MPH

Associate Professor (Clinical)
University of Utah School of Medicine
Pathologist
ARUP Laboratories

Dr. Gillian L. Hale is a medical director of anatomic pathology at ARUP Laboratories and an associate professor (clinical) at the University of Utah School of Medicine. Dr. Hale received her medical degree from George Washington University. She then completed an anatomic and clinical pathology residency and a gastrointestinal and liver pathology fellowship, both at the University of California at San Francisco. Dr. Hale is a member of the Binford-Dammin Society of Infectious Disease Pathologists. Her research interests include infections of the liver and gastrointestinal tract.

Objectives

After this presentation, participants will be able to:

  • Recognize patterns of inflammation in the liver that aid in the diagnosis of emerging and reemerging infectious diseases
  • Synthesize clinical and laboratory data to narrow the differential diagnosis and help determine the etiology of hepatitis
  • Utilize and interpret special and immunohistochemical stains in the diagnosis of liver infections in tissue sections

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories