Fine Needle Aspiration vs. Touch Preparation Cytology: Insights from Selected Case Presentations


Prognostication, treatment and management of many solid malignancies are rapidly evolving due in part to revolutionary changes in the molecular diagnostics field. The increased shift to minimally invasive diagnostic sampling techniques coupled with efforts to enhance utilization of more limited diagnostic tissue samples (“do more with less”) pose new challenges to the pathology laboratory team today. This educational session will 1) discuss some of the factors driving the trend toward increased use of limited small tissue samples, 2) highlight how rapid on-site evaluation (ROSE) is increasingly being used to optimize the adequacy assessment and triage of such small biopsy specimens, 3) compare the use of fine needle aspiration biopsy (FNAB) and touch preparation evaluation of needle core biopsy in ROSE and 4) illustrate how the synthesis and current application of this evolving body of medical knowledge, skills and attitudes have resulted in some lessons learned from selected clinical cases.

Originally presented on February 11, 2020 in Park City, Utah.

Lecture Presenter

Lesley C. Lomo, MD

Lesley C. Lomo, MD

Associate Professor of Pathology (Clinical)
University of Utah School of Medicine
Medical Director, Anatomic Pathology
ARUP Laboratories

Dr. Lomo is an associate professor of pathology at the University of Utah School of Medicine. She received her medical degree from Wayne State University School of Medicine in Detroit and completed her residency in anatomic and clinical pathology, as well as fellowships in women’s and perinatal pathology, breast pathology, and cytopathology at Brigham and Women’s Hospital in Boston. Dr. Lomo is board certified in anatomic and clinical pathology and cytopathology. She is a member of several professional organizations, including the United States and Canadian Academy of Pathology, the American Society for Clinical Pathology, and the International Society of Gynecological Pathologists. Her research interests include education techniques for pathology trainees and medical students, neoplastic and non-neoplastic endometrial pathology, and biomarkers of malignancy risk in preneoplastic epithelial breast disease.


After this presentation, participants will be able to:

  • Recognize the factors influencing the increasing trend toward small diagnostic biopsy procurement and diagnosis across selected tumor tissue types
  • Identify various types of cytologic preparations from tissue samples, in particular touch preparations, and how they compare to fine needle aspiration biopsy
  • Discuss the utility of ROSE in the adequacy assessment and triage of small tissue samples and how FNAB and touch preparation evaluation of needle core biopsies compare in ROSE
  • Discuss important insights gained from the use of ROSE illustrated by a series of selected cases

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories