An Infectious Cause of Acute Liver Injury


Acute liver injury has a wide variety of causes with a complex laboratory workup involving many different areas in the clinical laboratory including chemistry, immunology, and microbiology, as illustrated in this case presentation of acute Q fever hepatitis. The goal of this lecture is to review basic liver function and laboratory testing for acute liver injury, with an emphasis on testing for autoimmune hepatitis, Epstein-Barr virus, and Coxiella burnetii.

Originally published on June 5, 2023

Lecture Presenter

Skyler J. Simpson, MD

Skyler J. Simpson, MD

PGY-4 Pathology Resident
University of Utah School of Medicine

Dr. Skyler Simpson grew up in the Seattle area and attended Seattle Pacific University where he earned a bachelor of science degree in biochemistry. He then completed his medical degree at the University of Arizona College of Medicine-Tucson.


After this presentation, participants will be able to:

  • Discuss the interpretation of serologic testing for Epstein-Barr Virus
  • Describe the basic microbiology and transmission of Coxiella burnetii
  • Explain the serologic testing for Q fever and how we differentiate between acute and chronic infections

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories