Verification of Automated Urinalysis Instrumentation: Analytical and Clinical Considerations

 

Automated methods for urinalysis promise greater efficiency, increased throughput, and improved accuracy and precision over conventional methods. This presentation provides a brief overview of urinalysis methods and describes an approach to method validation of automated urinalysis instrumentation.

Originally presented on June 20, 2023, in Salt Lake City, Utah.

Lecture Presenter

Lauren N. Pearson, DO, MPH

Lauren N. Pearson, DO, MPH

Associate Professor (Clinical)
University of Utah School of Medicine
Chief Medical Officer
ARUP Laboratories at University of Utah Health

Dr. Lauren Pearson is the chief medical officer for ARUP Laboratories at University of Utah Health, laboratory director for several clinical laboratories at University of Utah Health, and an associate professor of pathology at the University of Utah School of Medicine. She received a master’s degree in public health and a medical degree from Touro University California. She then completed an anatomic and clinical pathology residency at the University of Vermont College of Medicine, where she also served as chief resident. Dr. Pearson is board certified in anatomic and clinical pathology. Her academic interests include population health, pathology education, quality management, quality control, analytic interferences, instrumentation, and laboratory stewardship.

Objectives

After this presentation, participants will be able to:

  • Describe the chemical and physical principles behind conventional (manual) and automated methods for urinalysis testing
  • List the studies required to document method performance required by Clinical Laboratory Improvement Amendments (CLIA)
  • Apply CLIA requirements for method validation/verification to document performance characteristics of automated urinalysis methods

Sponsored by:

University of Utah School of Medicine, Department of Pathology, and ARUP Laboratories